Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891680 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1MCL1GPR35GRIN2D | |
| SCHEMBL14020980 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4918988 | 0.80 | TDP1 (0.52) | ALDH1A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3951676 | 0.80 | MEN1 (0.42) | ALDH1A1TDP1MCL1GPR35GRIN2D | |
| SCHEMBL71098 | 0.79 | GPR35 (0.45) | ALDH1A1TDP1MCL1GPR35GRIN2D | |
| SCHEMBL487041 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1MCL1GPR35GRIN2D | |
| SCHEMBL5206322 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TDP1MCL1GPR35TSHR | |
| SCHEMBL1285396 | 0.75 | CYP3A4 (0.44) | ALDH1A1TDP1MCL1GPR35GRIN2D | |
| SCHEMBL31538467 | 0.75 | GPR35 (0.50) | ALDH1A1TDP1MCL1GPR35GRIN2D | |
| SCHEMBL31538466 | 0.75 | GPR35 (0.50) | ALDH1A1TDP1MCL1GPR35GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338537-B2 | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |