SCHEMBL9446580

SCHEMBL9446580

CCN(NC(N)=S)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 1/20 0.42
ALOX12 P18054 1/20 0.42
CRHBP P24387 1/20 0.42
HTT P42858 1/20 0.42
CRHR2 Q13324 1/20 0.42
TSHR P16473 2/20 0.41
GLA P06280 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.41
TYR P14679 1/20 0.41
TAS2R38 P59533 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28266025 0.98 ALDH1A1 (0.50) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL28059480 0.85 ALDH1A1 (0.45) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL15775370 0.83 ALDH1A1 (0.44) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL8652157 0.81 ALDH1A1 (0.50) ALDH1A1L3MBTL1MEN1KMT2AHTT
SCHEMBL11598307 0.80 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL29137131 0.79 ALDH1A1 (0.48) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL9615041 0.79 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL11170994 0.78 L3MBTL1 (0.61) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL28420044 0.76 ALDH1A1 (0.48) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL3797066 0.75 KMT2A (0.59) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929866-B Modified resin and resin composition 旭化成株式会社 2023-07-07 CN disclosed
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
CN-113929866-A Modified resin and resin composition 旭化成株式会社 2022-01-14 CN disclosed
CN-107629183-B Modified resin and resin composition 旭化成株式会社 2021-01-05 CN disclosed
CN-111205424-A Modified resin and resin composition 旭化成株式会社 2020-05-29 CN disclosed
CN-105358602-B modified resin and resin composition 旭化成株式会社 2018-12-04 CN disclosed
CN-107629183-A Modified resin and resin combination 旭化成株式会社 2018-01-26 CN disclosed
CN-105518043-A Co2 containing foams and related methods NOVOMER INC 2016-04-20 CN disclosed
CN-105358602-A Modified resin and resin composition ASAHI KASEI CHEMICALS CORP 2016-02-24 CN disclosed
CN-105229047-A High strength polyurethane foam compositions and methods NOVOMER INC 2016-01-06 CN disclosed
CN-104428370-A Adhesive composition and method NOVOMER INC 2015-03-18 CN disclosed
CN-103827207-A Aliphatic polycarbonates for polyurethanes NOVOMER INC 2014-05-28 CN disclosed
EP-0526472-A1 HOUSEHOLD GENERAL-PURPOSE ADHESIVE ON A POLYURETHANE BASIS. HENKEL KGAA (DE) 1993-02-10 EP disclosed
WO-1991015529-A1 HOUSEHOLD GENERAL-PURPOSE ADHESIVE ON A POLYURETHANE BASIS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-10-17 WO disclosed