Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446974 | 0.90 | SLC40A1 (0.60) | GAAF2ALDH1A1GPR119MEN1 | |
| SCHEMBL9447008 | 0.90 | GLO1 (0.62) | GLO1GAAGLRA3MMP2ALDH1A1 | |
| SCHEMBL9446958 | 0.84 | SLC40A1 (0.65) | GLO1FFAR4KMT2ACKS1BSKP2 | |
| SCHEMBL9446966 | 0.84 | GLRA3 (0.60) | GLO1GAAGLRA3F2MMP2 | |
| SCHEMBL10654161 | 0.83 | GAA (0.60) | GLO1GAAF2ALDH1A1HPGD | |
| SCHEMBL9447001 | 0.81 | GLO1 (0.75) | GLO1GLRA3MMP2ALDH1A1HPGD | |
| SCHEMBL9447198 | 0.80 | KMT2A (0.61) | GLO1GAAALDH1A1HPGDGPR119 | |
| SCHEMBL7208902 | 0.77 | KDM4E (0.54) | GAAGLRA3ALDH1A1HPGDMEN1 | |
| SCHEMBL9446984 | 0.77 | MEN1 (0.71) | GLO1GAAALDH1A1HPGDGPR119 | |
| SCHEMBL6978005 | 0.76 | GLO1 (1.00) | GLO1MMP2ALDH1A1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |