Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.65 |
| ▸ | BRAF | P15056 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447154 | 0.92 | SLC40A1 (0.65) | SLC40A1BRAFTSHRNR3C1PGR | |
| SCHEMBL9447041 | 0.86 | SLC40A1 (0.60) | SLC40A1BRAFTSHRNR3C1PGR | |
| SCHEMBL9446963 | 0.85 | SLC40A1 (0.61) | SLC40A1BRAFTSHRNR3C1PGR | |
| SCHEMBL10650464 | 0.85 | NR3C1 (0.60) | SLC40A1BRAFTSHRNR3C1PGR | |
| SCHEMBL9447092 | 0.84 | SLC40A1 (0.76) | SLC40A1KMT2ACLK1CKS1BSKP2 | |
| SCHEMBL9446972 | 0.84 | GLO1 (0.61) | SLC40A1KMT2ACKS1BSKP2GLO1 | |
| SCHEMBL9446974 | 0.81 | SLC40A1 (0.60) | SLC40A1BRAFKMT2A | |
| SCHEMBL7192418 | 0.79 | SLC40A1 (1.00) | SLC40A1KMT2ACLK1CKS1BSKP2 | |
| SCHEMBL1798710 | 0.79 | BRAF (0.78) | BRAFTSHRNR3C1PGRAR | |
| SCHEMBL9800662 | 0.78 | NR3C1 (0.52) | SLC40A1BRAFTSHRNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |