Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446962 | 0.84 | MRGPRX1 (0.49) | HPGDMRGPRX1ALDH1A1BRD4KDR | |
| SCHEMBL9447116 | 0.84 | AR (0.52) | ARHPGDLMNAMRGPRX1ALDH1A1 | |
| SCHEMBL8307237 | 0.79 | AR (0.56) | ARHPGDLMNAMRGPRX1KIT | |
| SCHEMBL9446952 | 0.77 | PGR (0.54) | ARHPGDLMNAALDH1A1MAPT | |
| SCHEMBL7220505 | 0.77 | AR (0.50) | ARHPGDLMNAMRGPRX1ALDH1A1 | |
| SCHEMBL9446988 | 0.76 | AR (0.48) | ARHPGDLMNAMRGPRX1KIT | |
| SCHEMBL9446951 | 0.74 | MAPT (0.46) | ARHPGDLMNAMRGPRX1KDM4E | |
| SCHEMBL7219583 | 0.74 | AR (0.51) | ARHPGDLMNAMRGPRX1ALDH1A1 | |
| SCHEMBL16133354 | 0.74 | PSMD14 (0.54) | HPGDLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL9446965 | 0.74 | TP53 (0.46) | LMNAALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |