Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446958 | 0.92 | SLC40A1 (0.65) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL9447041 | 0.86 | SLC40A1 (0.60) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL9447092 | 0.84 | SLC40A1 (0.76) | SLC40A1CLK1CKS1BSKP2KMT2A | |
| SCHEMBL9447051 | 0.84 | PGR (0.60) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL9447018 | 0.84 | PGR (0.67) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL9446948 | 0.84 | PGR (0.67) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL9447008 | 0.83 | GLO1 (0.62) | SLC40A1ARTSHRCKS1BSKP2 | |
| SCHEMBL9446963 | 0.81 | SLC40A1 (0.61) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL1472100 | 0.80 | PGR (0.71) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL9447198 | 0.80 | KMT2A (0.61) | SLC40A1PGRARTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |