SCHEMBL94490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL96038	0.81	HSD11B1 (0.62)	AGERMTNR1AHSD11B1MEN1KMT2A
	SCHEMBL95632	0.76	AGER (0.76)	AGERMTNR1AMEN1KMT2ASLC6A9
	SCHEMBL95169	0.72	ALDH1A1 (0.58)	MEN1KMT2AKDM4ELMNAALOX15
	SCHEMBL3178423	0.71	ITK (0.43)	F2ITKMEN1KMT2A
	SCHEMBL10722280	0.71	HSD11B1 (0.70)	AGERMTNR1AHSD11B1MEN1KMT2A
	SCHEMBL4486060	0.71	HSD11B1 (0.61)	AGERMTNR1AHSD11B1MEN1KMT2A
	SCHEMBL15492946	0.71	AGER (0.51)	AGERMTNR1AHSD11B1MEN1KMT2A
	SCHEMBL5475728	0.71	PYGL (0.39)	AGERF2PYGLALDH1A1
	SCHEMBL14534797	0.71	F2 (0.40)	F2ITKPYGLALDH1A1
	SCHEMBL8773489	0.71	ALDH1A1 (0.39)	AGERMTNR1AF2PYGLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.