Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449194 | 0.82 | ADRA2C (0.61) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL6743516 | 0.82 | ADRA2C (0.61) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL851371 | 0.82 | AOC3 (0.62) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8135905 | 0.82 | AOC3 (0.62) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| Hydrochloric Acid SCHEMBL3008842 | 0.81 | AOC3 (0.61) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL21278557 | 0.79 | AOC3 (0.54) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8125880 | 0.79 | AOC3 (0.54) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL9206136 | 0.78 | CSNK1E (0.55) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL9190252 | 0.78 | KDM4E (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL12418041 | 0.78 | KDM4E (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250546-A | Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0177245-B1 | AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0177245-A2 | Amino-alcohol derivatives and processes for their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |