Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759822 | 0.93 | SIGMAR1 (0.48) | SIGMAR1KCNJ1CYP2D6POLB | |
| SCHEMBL9449400 | 0.84 | HTR1A (0.55) | SIGMAR1 | |
| SCHEMBL8785466 | 0.83 | DRD2 (0.46) | KCNH2CYP1A2CYP2D6 | |
| SCHEMBL8785483 | 0.82 | HTR1A (0.48) | SIGMAR1KCNJ1KCNH2TMEM97 | |
| SCHEMBL7756732 | 0.81 | DRD2 (0.45) | SIGMAR1KCNJ1L3MBTL3 | |
| SCHEMBL7756751 | 0.80 | SIGMAR1 (0.44) | SIGMAR1KCNJ1KCNH2TMEM97 | |
| SCHEMBL8116069 | 0.78 | CCR3 (0.57) | SIGMAR1 | |
| SCHEMBL7763028 | 0.78 | SIGMAR1 (0.37) | SIGMAR1KCNJ1TMEM97 | |
| SCHEMBL8114275 | 0.77 | GRIN2B (0.49) | — | |
| SCHEMBL9449426 | 0.76 | SIGMAR1 (0.57) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | claimed |
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | disclosed |