SCHEMBL243575

SCHEMBL243575

N[C@@H](Cc1ccc(O)cc1)C(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.62
KMT2A Q03164 3/20 0.61
KDM4E B2RXH2 3/20 0.61
MAPT P10636 3/20 0.61
LMNA P02545 2/20 0.61
TSHR P16473 2/20 0.61
BLM P54132 2/20 0.61
PMP22 Q01453 2/20 0.61
MEN1 O00255 2/20 0.61
MPO P05164 1/20 0.61
HIF1A Q16665 1/20 0.61
SLC6A2 P23975 2/20 0.59
OPRM1 P35372 2/20 0.53
OPRD1 P41143 2/20 0.53
MIF P14174 1/20 0.52
ERAP1 Q9NZ08 4/20 0.52
ERAP2 Q6P179 3/20 0.52
LNPEP Q9UIQ6 2/20 0.52
HTR1A P08908 2/20 0.51
HTR2A P28223 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10359013 1.00 TACR1 (0.62) TACR1KMT2AKDM4EMAPTLMNA
Tyrosine SCHEMBL1065122 0.94 KMT2A (0.68) TACR1KMT2AKDM4EMAPTLMNA
SCHEMBL120931 0.91 KDM4E (0.69) TACR1KMT2AKDM4EMAPTLMNA
Tyrosine SCHEMBL9449484 0.91 KDM4E (0.63) TACR1KMT2AKDM4EMAPTLMNA
SCHEMBL289044 0.90 MAPT (0.74) TACR1KMT2AKDM4EMAPTLMNA
SCHEMBL475351 0.90 MAPT (0.74) TACR1KMT2AKDM4EMAPTLMNA
SCHEMBL2721523 0.88 BLM (0.67) TACR1KMT2AKDM4EMAPTLMNA
D-Tryptophan SCHEMBL10359012 0.88 KMT2A (0.80) TACR1KMT2AKDM4EMAPTLMNA
Tryptophan SCHEMBL6032938 0.88 KMT2A (0.80) TACR1KMT2AKDM4EMAPTLMNA
Tryptophan SCHEMBL15168746 0.88 KMT2A (0.80) TACR1KMT2AKDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083323-A1 A PEPTIDE AND THE SELECTION METHOD THEREOF THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2023-05-19 WO claimed
US-20100120721-A1 SUBSTITUTED PIPERIDINOPHENYL OXAZOLIDINONES WOCKHARDT RESEARCH CENTRE (IN) 2010-05-13 US claimed
US-20040244714-A1 Methods for growing and imprinting fish using an odorant MARICAL, INC. 2004-12-09 US claimed
US-6774213-B1 CONTAIN ONE MUTATIONS IN THE MAW (MAKES ATP WORK) MOTIF; MUTANTS RELY ON REPLACEMENT OF WILDTYPE AMINO ACID RESIDUES TO ALTER THE THREE-DIMENSIONAL STRUCTURE OF THE MAW MOTIF AND TO CHANGE THE PROTEIN'S DNA-BINDING PROPERTIES Roca, Alberto I. 2004-08-10 US claimed
US-6709835-B2 NUTRIENT BROTH FOR DETERMINING INTRACELLULAR ACTIVITY OF GLUTATHIONE IN LYMPHOCYTES CRAWFORD J FRED (US) 2004-03-23 US claimed
US-20030012817-A1 Oral drug delivery compositions and methods EMISPHERE TECHNOLOGIES, INC. 2003-01-16 US claimed
US-20020052422-A1 Oral drug delivery compositions and methods EMISPHERE TECHNOLOGIES, INC. 2002-05-02 US claimed
US-5935601-A Modified amino acids for drug delivery EMISPHERE TECHNOLOGIES, INC. (US) 1999-08-10 US claimed
US-5840918-A PEPTIDOMIMETIC COMPOUNDS USEFUL IN THE TREATMENT OF RAS-ASSOCIATED HUMAN CANCERS EISAI CO., LTD. (JP) 1998-11-24 US claimed
US-5792451-A AMINO ACID DERIVATIVES AS CARRIERS FOR SENSITIVE AGENTS SUCH AS BIOACTIVE PEPTIDES EMISPHERE TECHNOLOGIES, INC. (US) 1998-08-11 US claimed
EP-0758843-A4 MODIFIED AMINO ACIDS FOR DRUG DELIVERY EMISPHERE TECH INC (US) 1998-05-20 EP claimed
US-5686422-A Synthetic inhibitors of mammalian collagenase RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-11-11 US claimed
US-5629020-A Modified amino acids for drug delivery EMISPHERE TECHNOLOGIES, INC. (US) 1997-05-13 US claimed
EP-0758843-A1 MODIFIED AMINO ACIDS FOR DRUG DELIVERY Emisphere Technologies, Inc. (US) 1997-02-26 EP claimed
EP-0696208-A4 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS EMISPHERE TECH INC (US) 1997-01-29 EP claimed
EP-0696208-A1 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS Emisphere Technologies, Inc. (US) 1996-02-14 EP claimed
WO-1995028838-A1 MODIFIED AMINO ACIDS FOR DRUG DELIVERY EMISPHERE TECHNOLOGIES, INC. (US) 1995-11-02 WO claimed
WO-1994023767-A1 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS EMISPHERE TECHNOLOGIES, INC. (US) 1994-10-27 WO claimed
US-12553029-B2 Treatment of NSCLC patients with tumor infiltrating lymphocyte therapies IOVANCE BIOTHERAPEUTICS, INC. (US) 2026-02-17 US disclosed
WO-1997032984-A1 DIABETES MELLITUS 37 kD AUTOANTIGEN PROTEIN-TYROSINE PHOSPHATASE ZYMOGENETICS, INC. (US) 1997-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030012817-A1 Oral drug delivery compositions and methods PTMS, ADM2, DNPEP TACR1 895/4885KMT2A 1224/4885KDM4E 688/4885
US-20020052422-A1 Oral drug delivery compositions and methods ADM2, PTMS, DNPEP TACR1 962/4885KMT2A 887/4885KDM4E 303/4885
US-20100120721-A1 SUBSTITUTED PIPERIDINOPHENYL OXAZOLIDINONES CYP2C19, ALPI, CYP3A7 TACR1 2526/4885KMT2A 4463/4885KDM4E 3606/4885
US-12553029-B2 Treatment of NSCLC patients with tumor infiltrating lymphocyte therapies PDCD1LG2, CD274, PDCD1 TACR1 4318/4885KMT2A 2345/4885KDM4E 2331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.