Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583198 | 0.89 | KCNH2 (0.78) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11074672 | 0.86 | ADRB1 (0.76) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8353732 | 0.85 | DRD2 (0.77) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8785239 | 0.85 | KCNH2 (0.81) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9449410 | 0.83 | KCNH2 (0.60) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14340514 | 0.83 | DRD2 (1.00) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4525293 | 0.83 | KCNH2 (1.00) | KCNH2DRD2HTR1ADRD4 | |
| SCHEMBL1372924 | 0.81 | ADRB1 (0.65) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9670409 | 0.81 | DRD2 (0.68) | DRD2KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6824119 | 0.81 | KCNH2 (0.76) | KCNH2DRD2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | disclosed |