Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.77 |
| ▸ | HTR2C | P28335 | 5/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449797 | 0.83 | HTR1A (0.72) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL9449639 | 0.80 | HTR1A (0.72) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948066 | 0.80 | HTR1A (0.77) | HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL9449919 | 0.80 | HTR1A (0.98) | HTR1AHTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9437971 | 0.79 | HTR1A (0.98) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948018 | 0.78 | HTR1A (0.53) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL7759816 | 0.77 | SIGMAR1 (1.00) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL9449586 | 0.76 | SIGMAR1 (0.69) | HTR1AHTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9449678 | 0.75 | HTR1A (0.98) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL9449853 | 0.74 | HTR1A (0.86) | HTR1AHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | disclosed |