⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571300 | 0.79 | TSHR (0.59) | — | |
| SCHEMBL7539726 | 0.78 | TSHR (0.57) | — | |
| SCHEMBL12763781 | 0.77 | CYP1A2 (0.61) | — | |
| SCHEMBL6698873 | 0.75 | CYP1A2 (0.59) | — | |
| SCHEMBL84691 | 0.73 | — | — | |
| SCHEMBL19997205 | 0.71 | CYP1A2 (0.48) | — | |
| SCHEMBL10089552 | 0.69 | — | — | |
| SCHEMBL11583116 | 0.67 | CA2 (0.57) | — | |
| SCHEMBL2915082 | 0.65 | CA1 (0.66) | — | |
| SCHEMBL14401558 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641193-A4 | CHEMOTHERAPEUTIC DRUG COMBINATIONS. | MARTIN DANIEL S (US) | 1995-09-06 | — | — | EP | claimed |
| EP-0641193-A1 | CHEMOTHERAPEUTIC DRUG COMBINATIONS | PRO-NEURON, INC. (US) | 1995-03-08 | — | — | EP | claimed |
| WO-1993023014-A1 | CHEMOTHERAPEUTIC DRUG COMBINATIONS | MARTIN DANIEL S (US) | 1993-11-25 | — | — | WO | claimed |
| CN-109071526-B | Acid addition salts of piperazine derivatives | 阿森纽荣股份公司 | 2023-02-28 | — | — | CN | disclosed |
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| CN-109908124-A | Utilize the method for hyperuricemia in Halofenate or HALOFENIC ACID and the second uric acid depressant treatment patient with gout | 西玛贝医药公司 | 2019-06-21 | — | — | CN | disclosed |
| US-10137112-B2 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent | CYMABAY THERAPEUTICS, INC. (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180214420-A1 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent | CYMABAY THERAPEUTICS, INC. (US) | 2018-08-02 | — | — | US | disclosed |
| US-9801860-B2 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent | CYMABAY THERAPEUTICS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20160271111-A1 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent | CYMABAY THERAPEUTICS, INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9439891-B2 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent | CYMABAY THERAPEUTICS, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| EP-1878812-A1 | COPPER SURFACE TREATMENT METHOD AND COPPER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006135602-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | UNIVERSITY OF ROCHESTER (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20040082576-A1 | Malonyl-coa decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-0357783-B1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993023014-A1 | CHEMOTHERAPEUTIC DRUG COMBINATIONS | MARTIN DANIEL S (US) | 1993-11-25 | — | — | WO | disclosed |
| EP-0357783-A1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4357396-A | MIRRORS | PPG INDUSTRIES, INC. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4350804-A | Curable compositions comprising an azole-functional resin and a metal-ligand complex | PPG INDUSTRIES, INC. (US) | 1982-09-21 | — | — | US | disclosed |
| US-3949082-A | Thiadiazoles as anti-inflammatory agents | MERCK & CO., INC. (US) | 1976-04-06 | — | — | US | disclosed |