SCHEMBL9450756

SCHEMBL9450756

CC1=CC(C)(C)Nc2ccc(Cc3ccc4c(c3)C(C)=CC(C)(C)N4)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 1.00
▸ MAPT P10636 3/20 1.00
▸ TDP1 Q9NUW8 3/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ L3MBTL1 Q9Y468 2/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ ALDH1A1 P00352 7/20 0.79
▸ HPGD P15428 6/20 0.79
▸ GAA P10253 1/20 0.79
▸ HSD17B10 Q99714 5/20 0.67
▸ CYP3A4 P08684 3/20 0.63
▸ CYP1A2 P05177 2/20 0.63
▸ CYP2D6 P10635 2/20 0.63
▸ CYP2C9 P11712 2/20 0.63
▸ CYP2C19 P33261 2/20 0.63
▸ LMNA P02545 2/20 0.59
▸ ALOX15 P16050 1/20 0.59
▸ ALOX12 P18054 1/20 0.59
▸ HIF1A Q16665 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11728404 0.98 KDM4E (0.97) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL7071018 0.92 KDM4E (0.85) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL1323507 0.88 ALDH1A1 (1.00) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL7073326 0.85 ALDH1A1 (0.77) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL31395941 0.85 KDM4E (0.72) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL31396113 0.85 KDM4E (0.72) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL7071108 0.83 ALDH1A1 (0.73) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL31396217 0.82 KDM4E (0.67) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL1263211 0.82 ALDH1A1 (0.71) KDM4EMAPTTDP1MEN1KMT2A
SCHEMBL11349500 0.82 KDM4E (0.68) KDM4EMAPTTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3641641-B1 NON-CONTACT HEART RATE MONITORING GE PREC HEALTHCARE LLC (US) 2026-04-22 — — EP claimed
US-12559656-B2 Solvent-free moisture curing silicone conformal coating and preparation method thereof CHENGDU TALY TECHNOLOGY CO., LTD. (CN) 2026-02-24 — — US claimed
EP-4667696-A1 DRIVE WITH ABSOLUTE POSITION DETECTION GEZE GmbH (DE) 2025-12-24 — — EP claimed
EP-4634493-A1 SLIDING CAM AND SLIDING-CAM CAMSHAFT thyssenkrupp Dynamic Components GmbH (DE) 2025-10-22 — — EP claimed
EP-4601509-A1 ASSEMBLY COMPRISING A STATIONARY FURNITURE PART, A MOVABLE FURNITURE PART, AND A GUIDE DEVICE JULIUS BLUM GMBH (AT) 2025-08-20 — — EP claimed
EP-4584564-A1 SENSOR INTEGRATED CIRCUIT (IC) WITH OPPOSITE FACING AMBIENT LIGHT SENSOR AND PROXIMITY SENSOR, AND RELATED ELECTRONIC DEVICES AND FABRICATION METHODS QUALCOMM INCORPORATED (US) 2025-07-16 — — EP claimed
EP-4581245-A1 CYLINDER HEAD COVER, AND METHOD FOR INSTALLING A CYLINDER HEAD COVER thyssenkrupp Dynamic Components GmbH (DE) 2025-07-09 — — EP claimed
EP-3562429-B1 SYSTEM AND METHOD FOR DETERMINING STRUCTURAL CHARACTERISTICS OF AN OBJECT PERIMETRICS INC (US) 2025-07-02 — — EP claimed
CN-120143724-A Mariculture net cage management and control system 海南中船蓝泰海洋工程有限公司 2025-06-13 — — CN claimed
CN-114554627-B Communication method based on low-power consumption wireless sensor ad hoc network 四川菁能科技有限公司 2025-05-16 — — CN claimed
CN-216433073-U Portable photovoltaic module electrical and environmental data acquisition equipment 国网江苏省电力有限公司常州供电分公司 2022-05-03 — — CN claimed
CN-216410274-U Temperature and humidity measurement module capable of realizing networking data transmission 图灵微感科技(河北)有限公司 2022-04-29 — — CN claimed
CN-112021233-B Automatic feeding equipment for aquaculture industry 张晶 2022-04-01 — — CN claimed
EP-3649021-B1 PACKAGED RAIN SENSOR PAD MARCY ENTPR INC (US) 2022-03-30 — — EP claimed
CN-112212001-B Gear shifting force pre-compensation correction control method for gear shifting actuator of AMT (automated mechanical transmission) 株洲齿轮有限责任公司 2022-03-01 — — CN claimed
CN-215890154-U Analog quantity signal conversion device 无锡威孚力达催化净化器有限责任公司 2022-02-22 — — CN claimed
EP-3548022-A1 COMPOSITIONS FOR MODULATING PD-1 SIGNAL TRANSDUCTION Augusta University Research Institute, Inc. (US) 2019-10-09 — — EP claimed
US-20180153898-A1 COMPOSITIONS FOR MODULATING PD-1 SIGNAL TRANSDUCTION AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. 2018-06-07 — — US claimed
WO-2018100556-A1 COMPOSITIONS FOR MODULATING PD-1 SIGNAL TRANSDUCTION AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) 2018-06-07 — — WO claimed
US-4356306-A ANTITUMOR, ANTICARCINOGENIC MATERIAL VEGYIPARI SZOVETKEZET (HU) 1982-10-26 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559656-B2 Solvent-free moisture curing silicone conformal coating and preparation method thereof CDH1, DNMT3B, ITGB1 KDM4E 149/4885MAPT 4357/4885TDP1 738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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