Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581944 | 0.92 | KDM4E (0.39) | THRBTHRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23581926 | 0.87 | HTT (0.43) | THRBTHRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8387100 | 0.86 | ALDH1A1 (0.42) | THRBKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL29137109 | 0.85 | THRB (0.42) | THRBTHRAALDH1A1 | |
| SCHEMBL10441457 | 0.84 | THRA (0.37) | THRBTHRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8040122 | 0.83 | THRB (0.45) | THRBTHRAALDH1A1 | |
| SCHEMBL32678535 | 0.82 | THRB (0.46) | THRBTHRAALDH1A1 | |
| SCHEMBL32678536 | 0.82 | THRB (0.46) | THRBTHRAALDH1A1 | |
| SCHEMBL32678537 | 0.82 | THRB (0.46) | THRBTHRAALDH1A1 | |
| SCHEMBL10441454 | 0.80 | L3MBTL1 (0.39) | THRBTHRAALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536200-A1 | FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS. | MINNESOTA MINING & MFG (US) | 1993-04-14 | — | — | EP | disclosed |