Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450727 | 0.85 | FOLH1 (0.48) | FOLH1KDM4EELANEMCL1ALDH1A1 | |
| SCHEMBL9450684 | 0.84 | ALDH1A1 (0.54) | FOLH1KDM4EELANEMCL1ALDH1A1 | |
| SCHEMBL9450746 | 0.81 | FOLH1 (0.45) | FOLH1KDM4EELANEMCL1ALDH1A1 | |
| SCHEMBL9450663 | 0.80 | TLR9 (0.46) | FOLH1KDM4EELANEL3MBTL1PTGER1 | |
| SCHEMBL9450749 | 0.78 | ALOX15 (0.46) | ELANEMCL1PTGER1MRGPRX4 | |
| SCHEMBL24983867 | 0.72 | FOLH1 (0.65) | FOLH1KDM4EMCL1ALDH1A1POLB | |
| SCHEMBL30892473 | 0.72 | FOLH1 (0.65) | FOLH1KDM4EMCL1ALDH1A1POLB | |
| SCHEMBL10089235 | 0.71 | FOLH1 (0.69) | FOLH1KDM4EMCL1ALDH1A1POLB | |
| SCHEMBL28018441 | 0.71 | SRD5A1 (0.58) | FOLH1KDM4EELANEALDH1A1MRGPRX4 | |
| SCHEMBL28017860 | 0.71 | SRD5A1 (0.58) | FOLH1KDM4EELANEALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250691-A | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0531976-A1 | Heteroaryl derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1993-03-17 | — | — | EP | disclosed |