Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | UBE2M | P61081 | 1/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451652 | 0.89 | MCHR1 (0.48) | MCHR1ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL3958170 | 0.89 | ALDH1A1 (0.60) | MCHR1ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL3956758 | 0.88 | MCHR1 (0.61) | MCHR1LTA4HNPC1RAB9A | |
| Fumaric Acid SCHEMBL9451568 | 0.82 | MCHR1 (0.55) | MCHR1KMT2A | |
| Fumaric Acid SCHEMBL9451571 | 0.82 | MCHR1 (0.55) | MCHR1KMT2A | |
| SCHEMBL7309056 | 0.81 | MCHR1 (0.65) | MCHR1ALDH1A1MAPTLTA4HNPC1 | |
| SCHEMBL16517731 | 0.81 | LOXL2 (0.51) | ALDH1A1HTTMAPTSMN1; SMN2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL16506850 | 0.80 | LOXL2 (0.50) | ALDH1A1HTTMAPTSMN1; SMN2HSP90AA1 | |
| Fumaric Acid SCHEMBL9451679 | 0.79 | SIGMAR1 (0.52) | MCHR1ALDH1A1HTTMAPT | |
| Fumaric Acid SCHEMBL9451677 | 0.79 | SIGMAR1 (0.52) | MCHR1ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |