Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451629 | 0.89 | MCHR1 (0.59) | MCHR1MAPTALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL9451676 | 0.87 | USP2 (0.52) | MCHR1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9451538 | 0.87 | MAPT (0.48) | MCHR1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16517731 | 0.82 | LOXL2 (0.51) | MAPTALDH1A1SMN1; SMN2HSP90AA1HTT | |
| Fumaric Acid SCHEMBL9451606 | 0.81 | ALDH1A1 (0.47) | MCHR1MAPTALDH1A1CYP2D6CHRM1 | |
| Fumaric Acid SCHEMBL9451611 | 0.81 | ALDH1A1 (0.47) | MCHR1MAPTALDH1A1CYP2D6CHRM1 | |
| Hydrochloric Acid SCHEMBL16506850 | 0.80 | LOXL2 (0.50) | MAPTALDH1A1SMN1; SMN2HSP90AA1HTT | |
| Cadaverine Tartrate SCHEMBL9451528 | 0.80 | MCHR1 (0.44) | MCHR1SMN1; SMN2CYP2D6CHRM1HRH1 | |
| SCHEMBL9451716 | 0.80 | LSS (0.55) | MAPTCYP2D6CHRM1HRH1KMT2A | |
| SCHEMBL9451671 | 0.80 | MAPT (0.54) | MCHR1MAPTALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |