Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451684 | 0.93 | KDM4E (0.49) | MAPTGFERALDH1A1LMNAMAPK1 | |
| SCHEMBL9451716 | 0.87 | LSS (0.55) | MAPTCYP2D6HRH1CHRM1HRH3 | |
| SCHEMBL7310386 | 0.86 | MCHR1 (0.50) | MAPTGFERALDH1A1CYP2D6HRH1 | |
| SCHEMBL9451632 | 0.84 | KDM4E (0.57) | CYP2D6HRH1CHRM1KDM4EKCNH2 | |
| SCHEMBL9451676 | 0.83 | USP2 (0.52) | MAPTALDH1A1LMNAMAPK1CYP2D6 | |
| SCHEMBL9451538 | 0.83 | MAPT (0.48) | MAPTGFERALDH1A1LMNAMAPK1 | |
| SCHEMBL9451695 | 0.82 | POLB (0.59) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL9451652 | 0.80 | MCHR1 (0.48) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL9451529 | 0.80 | CHIA (0.54) | MAPTGFERALDH1A1LMNAMAPK1 | |
| Fumaric Acid SCHEMBL9451498 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1LMNACYP2D6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |