Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451538 | 0.91 | MAPT (0.48) | MCHR1CYP2D6CHRM1HRH1MEN1 | |
| SCHEMBL3956758 | 0.89 | MCHR1 (0.61) | USP2MCHR1LTA4HNPC1RAB9A | |
| SCHEMBL9451652 | 0.87 | MCHR1 (0.48) | MCHR1CYP2D6CHRM1HRH1LTA4H | |
| Cadaverine Tartrate SCHEMBL9451528 | 0.85 | MCHR1 (0.44) | MCHR1CYP2D6CHRM1HRH1NPY5R | |
| Fumaric Acid SCHEMBL9451498 | 0.84 | ALDH1A1 (0.47) | MCHR1CYP2D6CHRM1HRH1MEN1 | |
| Fumaric Acid SCHEMBL9451606 | 0.84 | ALDH1A1 (0.47) | MCHR1CYP2D6CHRM1HRH1MEN1 | |
| Fumaric Acid SCHEMBL9451496 | 0.84 | ALDH1A1 (0.47) | MCHR1CYP2D6CHRM1HRH1MEN1 | |
| Fumaric Acid SCHEMBL9451611 | 0.84 | ALDH1A1 (0.47) | MCHR1CYP2D6CHRM1HRH1MEN1 | |
| SCHEMBL9451671 | 0.83 | MAPT (0.54) | MCHR1CYP2D6CHRM1HRH1KMT2A | |
| SCHEMBL9451716 | 0.83 | LSS (0.55) | CYP2D6CHRM1HRH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |