Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451699 | 0.94 | SIRT6 (0.51) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9451694 | 0.86 | KCNJ1 (0.51) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL14183554 | 0.85 | KCNJ1 (0.50) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9451668 | 0.83 | MAPT (0.46) | MEN1KMT2AMAPTALDH1A1SIRT6 | |
| SCHEMBL9451638 | 0.82 | SIGMAR1 (0.51) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9451716 | 0.82 | LSS (0.55) | MEN1KMT2AMAPTKCNH2CYP2D6 | |
| SCHEMBL9451671 | 0.82 | MAPT (0.54) | KMT2AMAPTALDH1A1LMNAMAPK1 | |
| Fumaric Acid SCHEMBL9451729 | 0.81 | MEN1 (0.51) | POLBMEN1KMT2AMAPTALDH1A1 | |
| Fumaric Acid SCHEMBL7308310 | 0.81 | MEN1 (0.51) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7303500 | 0.81 | POLB (0.53) | POLBMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |