Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871483 | 0.77 | TAAR1 (0.45) | KCNJ1KCNH2LOXL2MAOAMAOB | |
| SCHEMBL917006 | 0.77 | CYP2D6 (0.42) | LOXL2CYP2A6HSD17B10CHRM3 | |
| SCHEMBL3683455 | 0.74 | CYP2D6 (0.44) | LOXL2CYP2A6HSD17B10CHRM3 | |
| SCHEMBL1004267 | 0.71 | LOXL2 (0.64) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL929380 | 0.68 | LOXL2 (0.67) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL10569888 | 0.67 | TSHR (0.68) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL9640908 | 0.67 | TSHR (0.62) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| Hydrochloric Acid SCHEMBL2588394 | 0.66 | LOXL2 (0.64) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| Bromide SCHEMBL28682315 | 0.66 | LOXL2 (0.64) | KCNJ1KCNH2LOXL2CYP2A6TSHR | |
| SCHEMBL8433294 | 0.66 | MAOA (0.60) | KCNJ1KCNH2LOXL2CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206240-A | Antiarrhythmia agents | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |