Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451673 | 0.63 | DYRK1A (0.35) | — | |
| SCHEMBL9451612 | 0.57 | PDPK1 (0.41) | — | |
| SCHEMBL9451618 | 0.56 | ADORA2A (0.37) | KDM4E | |
| SCHEMBL25694553 | 0.52 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL12221454 | 0.51 | LMNA (0.32) | — | |
| SCHEMBL26054506 | 0.51 | CNR2 (0.53) | KDM4EALDH1A1 | |
| SCHEMBL24735553 | 0.50 | LRRK2 (0.40) | — | |
| SCHEMBL27420022 | 0.50 | GFER (0.32) | ALDH1A1 | |
| SCHEMBL18997275 | 0.49 | HCAR3 (0.53) | ALDH1A1 | |
| SCHEMBL26054475 | 0.49 | ALDH1A1 (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567223-A1 | Glutamic acid derivatives as antineoplastic agents | ELI LILLY AND COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5196424-A | Antitumor | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |