Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451695 | 0.94 | POLB (0.59) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9451694 | 0.92 | KCNJ1 (0.51) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14183554 | 0.91 | KCNJ1 (0.50) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9451668 | 0.88 | MAPT (0.46) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9451638 | 0.87 | SIGMAR1 (0.51) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9451729 | 0.87 | MEN1 (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| Fumaric Acid SCHEMBL7308310 | 0.87 | MEN1 (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8491801 | 0.86 | CRHBP (0.54) | — | |
| SCHEMBL3440216 | 0.83 | MAPT (0.59) | SIRT6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10036175 | 0.83 | MAPT (0.53) | SIRT6MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |