Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451942 | 0.87 | GRM6 (0.45) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL10449750 | 0.81 | PPARD (0.49) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL10801295 | 0.76 | ALDH1A1 (0.54) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL10797270 | 0.76 | PPARG (0.61) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL11562896 | 0.75 | ALDH1A1 (0.58) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL10449749 | 0.75 | PTGDR2 (0.47) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL10969883 | 0.74 | PPARG (0.66) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| SCHEMBL9451884 | 0.73 | PTGS2 (0.58) | PTGS2MAPTALDH1A1GAAKDM4E | |
| SCHEMBL11561024 | 0.73 | ALDH1A1 (0.55) | PTGS2PTGDR2MAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9451973 | 0.73 | NPC1 (0.48) | PTGS2PTGDR2MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229386-A | Anticoagulants, hypotensive agents, antiallergens, antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5145860-A | Anticoagulants, vasodilators, antiinflammatory, antiallergens, enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0388909-A2 | Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |