Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FSHR | P23945 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 7/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427803 | 0.84 | FSHR (0.42) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL9453763 | 0.81 | CYP2C19 (0.49) | ALDH1A1TDP1TSHRRXRARXRB | |
| SCHEMBL503853 | 0.80 | MEN1 (0.46) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL29436894 | 0.80 | MEN1 (0.46) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| Water SCHEMBL27831248 | 0.79 | MEN1 (0.45) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL11156140 | 0.77 | NR3C1 (0.40) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL21427236 | 0.77 | GABRA1 (0.37) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL17931721 | 0.77 | TP53 (0.43) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL11165344 | 0.77 | FTO (0.43) | MAPTPLIN1ALDH1A1PLIN5ABHD5 | |
| SCHEMBL9453716 | 0.75 | CYP2C19 (0.43) | MAPTPLIN1ALDH1A1PLIN5ABHD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210353-A | Transarylalkylation | AMOCO CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |