Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 9/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022717 | 0.78 | KDM4E (0.48) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL1412268 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL6232605 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL20022719 | 0.73 | KDM4E (0.48) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL31288017 | 0.73 | CA1 (0.44) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL292306 | 0.70 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL8596062 | 0.69 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL8394428 | 0.68 | KDM4E (0.47) | ALDH1A1LMNAMAPTKDM4EDDAH1 | |
| SCHEMBL19198961 | 0.67 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTKDM4EPARP1 | |
| SCHEMBL26078 | 0.67 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTKDM4EDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187265-A | Medical diagnosis | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5187105-A | Process for determining thiols using chromogenic benzoisothiazolone derivatives | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |