Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455748 | 0.68 | ALDH1A1 (0.50) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL1661350 | 0.68 | GABRA1 (0.48) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| SCHEMBL19020845 | 0.68 | GPR3 (0.68) | KDM4ELMNAMAPTPDPK1CA12 | |
| SCHEMBL29412500 | 0.67 | TNKS2 (0.55) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL20022717 | 0.67 | KDM4E (0.48) | KDM4EDDAH1ALDH1A1LMNAMAPT | |
| SCHEMBL12505248 | 0.67 | PARP1 (0.47) | KDM4EALDH1A1LMNAPDPK1CA12 | |
| SCHEMBL29421129 | 0.67 | PARP1 (0.55) | KDM4EALDH1A1LMNAPDPK1CA12 | |
| SCHEMBL15264243 | 0.67 | NCF1 (0.44) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL2021911 | 0.66 | PARP1 (0.47) | KDM4EPDPK1CA12PARP1ALOX15 | |
| SCHEMBL31322342 | 0.66 | PARP1 (0.68) | KDM4EPDPK1CA12PARP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889034-A | ANTIINFLAMMATORY AGENT; ANTIATHEROSCLEROSIS AGENT; VIRICIDES | WARNER-LAMBERT COMPANY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5733921-A | ANTIRETROVIRAL AGENTS; ANTIINFLAMMATORY AGENTS; ANTIATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1998-03-31 | — | — | US | disclosed |