Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26143882 | 0.79 | ALDH1A1 (0.47) | NCF1IP6K1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL9456475 | 0.75 | ALDH1A1 (0.39) | IP6K1TSHRL3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9455796 | 0.73 | IP6K1 (0.37) | IP6K1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL22270616 | 0.73 | ALDH1A1 (0.44) | NCF1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9455892 | 0.72 | IP6K1 (0.38) | IP6K1TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL31128265 | 0.71 | L3MBTL1 (0.39) | NCF1TSHRL3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9455800 | 0.71 | IP6K1 (0.38) | IP6K1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL20424608 | 0.70 | MAPT (0.45) | NCF1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL31128227 | 0.69 | CHRNB2 (0.37) | NCF1IP6K1TSHRL3MBTL1MAPT | |
| SCHEMBL30811705 | 0.69 | CHRNB2 (0.49) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250527-A | Enzyme inhibitors; administering to reduce gastric acid secretion | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-10-05 | — | — | US | disclosed |
| EP-0184322-B1 | BENZIMIDAZOLES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0184322-A1 | Benzimidazoles | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |