Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455892 | 0.98 | IP6K1 (0.38) | ALDH1A1MAPTMEN1KMT2AIP6K1 | |
| Hydrochloric Acid SCHEMBL9455796 | 0.83 | IP6K1 (0.37) | ALDH1A1MAPTMEN1KMT2AIP6K1 | |
| Hydrochloric Acid SCHEMBL9455800 | 0.81 | IP6K1 (0.38) | ALDH1A1MAPTMEN1KMT2AIP6K1 | |
| SCHEMBL9455859 | 0.75 | NCF1 (0.44) | ALDH1A1MAPTMEN1KMT2AIP6K1 | |
| SCHEMBL10522829 | 0.72 | OPRK1 (0.43) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL28266208 | 0.70 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL17221263 | 0.69 | UBE2T (0.40) | ALDH1A1MAPTLMNANPSR1ALOX12 | |
| SCHEMBL10568183 | 0.68 | SMN1; SMN2 (0.49) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24126296 | 0.67 | UBE2T (0.41) | ALDH1A1MAPTIP6K1LMNANPSR1 | |
| SCHEMBL19996086 | 0.67 | HRH4 (0.50) | ALDH1A1MAPTMEN1KMT2AIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250527-A | Enzyme inhibitors; administering to reduce gastric acid secretion | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-10-05 | — | — | US | disclosed |
| EP-0184322-B1 | BENZIMIDAZOLES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0184322-A1 | Benzimidazoles | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |