Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427047 | 0.87 | ALDH1A1 (0.50) | POLBRAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL9710287 | 0.79 | POLB (0.46) | POLBRAB9AHTTSMN1; SMN2MAPT | |
| SCHEMBL9457601 | 0.78 | KCNH2 (0.47) | POLBRAB9AHTTSMN1; SMN2MAPT | |
| SCHEMBL9457588 | 0.78 | RAB9A (0.47) | POLBRAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL9710430 | 0.77 | RAB9A (0.44) | POLBRAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL9710427 | 0.77 | RAB9A (0.44) | POLBRAB9AHTTGAAMAPT | |
| SCHEMBL4834573 | 0.77 | RAB9A (0.51) | POLBRAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL4825899 | 0.74 | POLB (0.49) | POLBRAB9AGAAMAPTLOXL2 | |
| SCHEMBL13844980 | 0.73 | PPARD (0.44) | GAAMAPTCDK2NPC1ALDH1A1 | |
| SCHEMBL44366 | 0.73 | POLB (0.76) | POLBSMN1; SMN2MAPTLMNALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |