Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769472 | 0.83 | ALOX15 (0.48) | ALOX15GAAMGAMSIMGAM2 | |
| SCHEMBL14444174 | 0.79 | ALOX15 (0.44) | ALOX15GAAMGAMSIMGAM2 | |
| SCHEMBL15219640 | 0.78 | GAA (0.42) | ALOX15GAAMGAMSIMGAM2 | |
| SCHEMBL2482646 | 0.76 | GAA (0.59) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL2651973 | 0.76 | ALDH1A1 (0.46) | ALOX15GAAMGAMSIMGAM2 | |
| SCHEMBL1912605 | 0.76 | EGLN1 (0.63) | ALOX15GAAMGAMSIMGAM2 | |
| SCHEMBL602822 | 0.75 | — | — | |
| SCHEMBL11184401 | 0.74 | ALDH1A1 (0.56) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL9129733 | 0.74 | GAA (0.42) | ALOX15GAAMGAMSIMGAM2 | |
| SCHEMBL12467409 | 0.74 | GAA (0.42) | ALOX15GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |