Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 5/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710192 | 0.88 | LDHA (0.37) | MAPTALDH1A1HPGDHTTPOLB | |
| SCHEMBL9457533 | 0.88 | MAPT (0.40) | MAPTALDH1A1HPGDHTTKDM4E | |
| SCHEMBL9457524 | 0.79 | MAPT (0.40) | MAPTALDH1A1HTTPOLBGAA | |
| SCHEMBL9710035 | 0.75 | MEN1 (0.39) | MAPTALDH1A1HPGDHTT | |
| SCHEMBL9710210 | 0.75 | COPS5 (0.37) | MAPTALDH1A1HPGDSHMT2HTT | |
| SCHEMBL9457502 | 0.71 | PPID (0.42) | MAPTALDH1A1HPGDSHMT2POLB | |
| SCHEMBL9458088 | 0.71 | CYP3A4 (0.38) | ALDH1A1HTTPOLBKDM4ETDP1 | |
| SCHEMBL418873 | 0.71 | CYP1A2 (0.46) | MAPTALDH1A1HTTPOLBPTGDR2 | |
| SCHEMBL9710206 | 0.70 | COPS5 (0.36) | — | |
| SCHEMBL9458127 | 0.70 | HTT (0.40) | ALDH1A1HTTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |