Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PLTP | P55058 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457533 | 0.89 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9710192 | 0.87 | LDHA (0.37) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL9457392 | 0.76 | PLTP (0.42) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9457443 | 0.76 | AOC3 (0.52) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9458014 | 0.75 | MAPT (0.42) | MAPTALDH1A1HPGDHTT | |
| SCHEMBL9457465 | 0.75 | POLB (0.42) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9457594 | 0.73 | POLB (0.39) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9710527 | 0.73 | MAPT (0.42) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9710287 | 0.72 | POLB (0.46) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9458234 | 0.72 | MEN1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |