Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458418 | 0.79 | MAP3K12 (0.35) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3158074 | 0.75 | SLC6A3 (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31441151 | 0.74 | SLC6A3 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3516067 | 0.74 | SLC6A3 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31441140 | 0.74 | SLC6A3 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9458299 | 0.73 | MAOB (0.35) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL9457966 | 0.73 | CYP19A1 (0.37) | ALDH1A1MEN1KMT2ACYP19A1MAOA | |
| SCHEMBL626219 | 0.72 | SLC6A3 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15863054 | 0.72 | SLC6A4 (0.37) | WDR5NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9458506 | 0.71 | MLYCD (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |