Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458496 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9457966 | 0.78 | CYP19A1 (0.37) | MAOBMAOAMEN1ALDH1A1KMT2A | |
| SCHEMBL21854601 | 0.77 | NOTUM (0.37) | PTPRCPTPN1RXRARXRGRXRB | |
| SCHEMBL9458506 | 0.76 | MLYCD (0.47) | MEN1ALDH1A1KMT2AS1PR1S1PR3 | |
| SCHEMBL15207303 | 0.73 | MAOB (0.42) | MAOBMAOAMCL1 | |
| SCHEMBL9458055 | 0.73 | WDR5 (0.34) | MAOBMAOAMEN1ALDH1A1KMT2A | |
| SCHEMBL246959 | 0.71 | TAAR1 (0.48) | MAOBALDH1A1KMT2A | |
| SCHEMBL9458604 | 0.71 | CYP2A6 (0.40) | PTPN1MEN1ALDH1A1KMT2AS1PR1 | |
| SCHEMBL7594667 | 0.69 | RXRA (0.54) | MAOBRXRARXRGRXRB | |
| SCHEMBL9168708 | 0.68 | MAOA (0.55) | MAOBMAOAALDH1A1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |