Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458422 | 0.80 | HTR1A (0.31) | ALOX5 | |
| SCHEMBL9270185 | 0.79 | HPGD (0.40) | ALOX5 | |
| SCHEMBL9458357 | 0.78 | ALOX5 (0.41) | CYP1A2CYP2A6ALOX5 | |
| SCHEMBL9380439 | 0.78 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL9269765 | 0.77 | LMNA (0.36) | ALOX5 | |
| SCHEMBL9458188 | 0.72 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9084952 | 0.70 | MAP2K2 (0.34) | CYP1A2ALOX5 | |
| SCHEMBL9101868 | 0.70 | P2RX7 (0.37) | ALOX5 | |
| SCHEMBL9458698 | 0.69 | CYP2A6 (0.46) | CYP1A2CYP2A6RHEB | |
| SCHEMBL9084888 | 0.69 | PTPN11 (0.34) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |