Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781493 | 0.91 | LMNA (0.63) | GAATSHRKMT2AMEN1LMNA | |
| SCHEMBL9104852 | 0.84 | GAA (0.71) | GAATSHRKMT2AMEN1HTT | |
| SCHEMBL10397498 | 0.84 | PDK1 (0.59) | GAATSHRKMT2AMEN1HTT | |
| SCHEMBL1003665 | 0.84 | KMT2A (0.83) | GAATSHRKMT2AMEN1HDAC1 | |
| SCHEMBL11187328 | 0.83 | KMT2A (0.66) | KMT2AMEN1HDAC1HDAC6MAPT | |
| SCHEMBL9763463 | 0.82 | HTT (0.56) | GAATSHRHTTLMNAHDAC1 | |
| SCHEMBL2797137 | 0.81 | HTT (0.56) | GAATSHRHTTPLOD2NPC1 | |
| SCHEMBL30452096 | 0.81 | GAA (0.63) | GAATSHRKMT2AMEN1HTT | |
| SCHEMBL30801380 | 0.81 | GAA (0.52) | GAATSHRKMT2AMEN1HTT | |
| SCHEMBL5890987 | 0.81 | LMNA (0.69) | GAATSHRKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012087-A1 | BIS(CARBAMOYLPIPERIDYL)ALKYLENES AS PLATELET AGGREGATION INHIBITORY AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| US-5219867-A | Platelet aggregation inhibitory agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-15 | — | — | US | disclosed |