Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458222 | 0.85 | ALOX5 (0.36) | ALOX5MAPTPTGIRGRIN2BOGA | |
| SCHEMBL9385364 | 0.84 | MAPT (0.40) | ALOX5HSD11B1MAPTPTGIRGRIN2B | |
| SCHEMBL9380123 | 0.83 | ALOX5 (0.39) | ALOX5HSD11B1 | |
| SCHEMBL9457985 | 0.75 | PTGIR (0.39) | MAPTPTGIRLMNAHTR1AHTR3A | |
| SCHEMBL24270129 | 0.73 | HRH3 (0.37) | ALOX5MAPTOGALMNA | |
| SCHEMBL9458637 | 0.73 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9380947 | 0.71 | GRIN2B (0.32) | ALOX5GRIN2B | |
| SCHEMBL9083286 | 0.70 | P4HB (0.32) | — | |
| SCHEMBL29548263 | 0.70 | HTR1D (0.39) | ALOX5OGALMNA | |
| SCHEMBL24270086 | 0.70 | HTR1D (0.39) | ALOX5OGALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |