Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458067 | 0.88 | PTGIR (0.35) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL9458566 | 0.85 | MAOA (0.47) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL19532057 | 0.85 | TSHR (0.46) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL9457999 | 0.83 | MEN1 (0.46) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL2271509 | 0.82 | TSHR (0.52) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL9458464 | 0.75 | ALOX5 (0.32) | PTGIRHTR1AHTR3ALMNAMAPT | |
| SCHEMBL2754910 | 0.74 | ALDH1A1 (0.47) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL12733318 | 0.74 | TSHR (0.71) | PTGIRTSHRALDH1A1LMNATYR | |
| SCHEMBL22653014 | 0.73 | BCHE (0.39) | PTGIRTSHRHTR1AHTR3AALDH1A1 | |
| SCHEMBL15184102 | 0.73 | LMNA (0.43) | PTGIRTSHRHTR1AHTR3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |