Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 13/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 13/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 13/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125187 | 0.78 | ADORA2A (0.59) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL887808 | 0.75 | ADORA2A (0.59) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL385843 | 0.75 | ADORA2A (0.55) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL5857627 | 0.73 | GSK3B (0.53) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL5146335 | 0.72 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL1272854 | 0.72 | ADORA2A (0.51) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL9156685 | 0.72 | SLC22A6 (0.46) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL23834271 | 0.71 | ADORA2A (0.58) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL2698569 | 0.71 | ADORA2A (0.50) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL5694209 | 0.71 | GSK3B (0.61) | PI4KAPI4K2BPI4K2API4KBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1938430-A | Methods and devices for using raman-active probe constructs to assay biological samples | INTEL CORP (US) | 2007-03-28 | — | — | CN | disclosed |
| US-5204456-A | Derivatives of nucleosides and their use for the synthesis of oligonucleotides | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-04-20 | — | — | US | disclosed |
| US-4980460-A | Protected nucleosides which permit more efficient oligonucleotide syntheses | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1990-12-25 | — | — | US | disclosed |