Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535814 | 0.71 | KMT2A (0.38) | KMT2AMEN1PTGESALOX5KDM4E | |
| SCHEMBL10948857 | 0.68 | CSNK2B (0.48) | KMT2AMEN1ALOX5KDM4ELMNA | |
| SCHEMBL9458606 | 0.68 | ALOX5 (0.53) | KMT2AMEN1PTGESALOX5PTGS1 | |
| SCHEMBL1514634 | 0.67 | KMT2A (0.76) | KMT2AMEN1PTGESALOX5KDM4E | |
| SCHEMBL9458734 | 0.67 | PTGES (0.65) | PTGESALOX5PTGS1 | |
| SCHEMBL7001656 | 0.67 | KMT2A (0.52) | KMT2AMEN1PTGESALOX5KDM4E | |
| SCHEMBL6475789 | 0.66 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL6475197 | 0.66 | KMT2A (0.70) | KMT2AMEN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL10951911 | 0.66 | KMT2A (0.45) | KMT2AMEN1PTGESALOX5KDM4E | |
| SCHEMBL10957000 | 0.66 | KMT2A (0.45) | KMT2AMEN1PTGESALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260451-A | Enzyme inhibitors | MERCKLE GMBH (DE) | 1993-11-09 | — | — | US | disclosed |