Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440823 | 0.87 | MEN1 (0.59) | KDM4EMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9441057 | 0.85 | ALDH1A1 (0.48) | KDM4EMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9440912 | 0.82 | TSHR (0.49) | KDM4EMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9440733 | 0.77 | S1PR1 (0.40) | KDM4EMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4329577 | 0.75 | ENPP3 (0.46) | KDM4EALOX15MAPTENPP3HPGD | |
| SCHEMBL9441026 | 0.74 | TSHR (0.58) | KDM4ECYP2C9S1PR1S1PR3TSHR | |
| SCHEMBL4333153 | 0.74 | TSHR (0.46) | KDM4EMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL10435551 | 0.73 | TSHR (0.44) | KDM4EKMT2AS1PR1S1PR3TSHR | |
| SCHEMBL13732755 | 0.73 | ENPP3 (0.56) | S1PR1S1PR3SMN1; SMN2MAPTENPP3 | |
| SCHEMBL3180487 | 0.73 | NPC1 (0.45) | KDM4EMEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239080-A | Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0382199-A1 | Oxazole compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-16 | — | — | EP | disclosed |