Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | NT5E | P21589 | 3/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986206 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL9459478 | 0.82 | NPC1 (0.50) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL9799660 | 0.78 | RAPGEF4 (0.44) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL13901754 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL7564333 | 0.76 | RAPGEF4 (0.51) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL17491048 | 0.75 | HDAC2 (0.47) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL9342516 | 0.75 | RAPGEF4 (0.41) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL11781579 | 0.75 | MAPT (0.47) | ALDH1A1GAAMAPTPTPN1GPR35 | |
| SCHEMBL11340190 | 0.74 | GPR35 (0.49) | ALDH1A1TDP1KDM4EPOLBGAA | |
| SCHEMBL10878675 | 0.74 | GAA (0.77) | ALDH1A1TDP1KDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206426-A | Phenylene diamines and process for the preparation of phenylene diamines | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| US-5117050-A | PHENYLENE DIAMINES AND PROCESS FOR THE PREPARATION OF PHENYLENE DIAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |