Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CASP6 | P55212 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830815 | 0.87 | RAPGEF4 (0.59) | NPC1RAPGEF4ALDH1A1CASP6KDM4E | |
| SCHEMBL31219804 | 0.87 | L3MBTL1 (0.51) | NPC1ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL11358245 | 0.87 | CA1 (0.53) | NPC1ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL17491048 | 0.82 | HDAC2 (0.47) | NPC1RAPGEF4ALDH1A1CASP6KDM4E | |
| SCHEMBL9459840 | 0.82 | ALDH1A1 (0.48) | RAPGEF4ALDH1A1CASP6KDM4EMAPT | |
| SCHEMBL14678160 | 0.82 | NT5E (0.58) | NPC1ALDH1A1CASP6KMT2AMEN1 | |
| SCHEMBL8592935 | 0.81 | CASP6 (0.61) | NPC1ALDH1A1CASP6KDM4EMAPT | |
| SCHEMBL16272370 | 0.81 | ENPP2 (0.57) | NPC1ALDH1A1CASP6KDM4EMAPT | |
| SCHEMBL7564333 | 0.81 | RAPGEF4 (0.51) | RAPGEF4ALDH1A1CASP6KDM4EMAPT | |
| SCHEMBL9811326 | 0.80 | CA2 (0.47) | NPC1ALDH1A1KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333656-A1 | Reactive dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | claimed |
| CN-103554977-A | Golden yellow reactive dye | TIANJIN DEKAI CHEM IND CO LTD | 2014-02-05 | — | — | CN | disclosed |
| US-5206426-A | Phenylene diamines and process for the preparation of phenylene diamines | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0396077-B1 | PHENYLENE DIAMINES AND A PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1993-04-07 | — | — | EP | disclosed |
| US-5118826-A | Colorfastness | CIBA-GEIGY CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| US-5117050-A | PHENYLENE DIAMINES AND PROCESS FOR THE PREPARATION OF PHENYLENE DIAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-5021557-A | Copper-containing formazan dye, colorfast blue shades on cellulose | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0396077-A1 | Phenylene diamines and a process for their preparation | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0333656-A1 | Reactive dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | disclosed |
| EP-0315585-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |
| EP-0122881-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-08-13 | — | — | EP | disclosed |
| US-4545785-A | FIBER-REACTIVE DYES FOR CELLULOSE | CIBA-GEIGY CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| US-4504273-A | MONOAZO, TRIAZINE | CIBA-GEIGY CORPORATION (US) | 1985-03-12 | — | — | US | disclosed |
| EP-0122881-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-24 | — | — | EP | disclosed |
| EP-0105027-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-04-04 | — | — | EP | disclosed |
| EP-0012716-B1 | MONOCHLOROTRIAZINE DYESTUFFS OF THE PYRAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING TEXTILE MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-15 | — | — | EP | disclosed |
| US-4348318-A | DYEING AND PRINTING TEXTILES; MONOAZO, TRIAZINE, HYDRAZONE, AND PYRAZOLONE DYES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0012716-A1 | Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials | CIBA-GEIGY AG (CH) | 1980-06-25 | — | — | EP | disclosed |
| US-4138558-A | Anthraquinone compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1979-02-06 | — | — | US | disclosed |
| US-4035350-A | Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |