Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324373 | 0.91 | FFAR1 (0.41) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11208198 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL17766185 | 0.74 | FFAR1 (0.39) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11264686 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11573748 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11208151 | 0.71 | OPRM1 (0.39) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL9463334 | 0.70 | MEN1 (0.30) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15116699 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL9845391 | 0.69 | CYP2C19 (0.44) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL3150010 | 0.69 | SLC22A12 (0.50) | ALDH1A1HPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177211-A | Anti-platelet aggregation and anti-hypotensive | ALTER, S.A. (ES) | 1993-01-05 | — | — | US | disclosed |
| EP-0325187-B1 | 4-ALKYL-1, 4-DIHYDROPYRIDINES WITH PAF-ANTAGONIST ACTIVITY | ALTER, S.A. (ES) | 1992-11-11 | — | — | EP | disclosed |
| EP-0325187-A1 | 4-alkyl-1, 4-dihydropyridines with PAF-antagonist activity | ALTER, S.A. (ES) | 1989-07-26 | — | — | EP | disclosed |