Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630052 | 0.75 | CYP2C19 (0.43) | CYP2C19HIF1AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8324373 | 0.73 | FFAR1 (0.41) | FFAR1ALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL10079038 | 0.72 | ALDH1A1 (0.32) | ALDH1A1HPGDPKMSMN1; SMN2MEN1 | |
| SCHEMBL17766185 | 0.72 | FFAR1 (0.39) | CYP2C19HIF1AFFAR1ALDH1A1HPGD | |
| SCHEMBL24484042 | 0.70 | MAPT (0.40) | CYP2C19ALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL4592580 | 0.70 | ALDH1A1 (0.41) | FFAR1ALDH1A1HPGDPKMMEN1 | |
| SCHEMBL719566 | 0.70 | TGM2 (0.40) | CYP2C19ALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL11211696 | 0.69 | OPRM1 (0.42) | FFAR1ALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL9463528 | 0.69 | ALDH1A1 (0.38) | FFAR1ALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL16016898 | 0.68 | ALDH1A1 (0.47) | CYP2C19HIF1AFFAR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420266-A2 | Chromene or thiochromene derivatives, process for preparing the same, intermediate therefor, pharmaceutical compositions containing said derivatives and the use of said derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |