Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211696 | 0.91 | OPRM1 (0.42) | OPRM1DRD3DRD2ALDH1A1HPGD | |
| SCHEMBL11208198 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11264686 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11204292 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10523948 | 0.72 | HSD17B10 (0.48) | ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL9463528 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL15116699 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL6688633 | 0.69 | MAPT (0.43) | ALDH1A1HPGDFFAR1SMN1; SMN2MAPT | |
| SCHEMBL8324373 | 0.68 | FFAR1 (0.41) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 | |
| SCHEMBL11201978 | 0.68 | LMNA (0.43) | ALDH1A1HPGDMTNR1AMTNR1BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029719-B1 | VULCANIZABLE RUBBER COMPOSITIONS INHIBITED FROM PREMATURE VULCANIZATION BY METHYLENE THIOETHERS, AND NOVEL METHYLENE THIOETHERS | MONSANTO COMPANY (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |