Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259370 | 0.82 | PKM (0.42) | MAPTRAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL2994051 | 0.78 | NPC1 (0.52) | MAPTPEPDALDH1A1NPC1MEN1 | |
| SCHEMBL2995603 | 0.78 | PEPD (0.35) | MAPTPEPDALDH1A1NPC1MEN1 | |
| SCHEMBL3884988 | 0.78 | ALDH1A1 (0.52) | MAPTPEPDALDH1A1NPC1MEN1 | |
| SCHEMBL2993188 | 0.78 | PEPD (0.35) | MAPTPEPDALDH1A1NPC1MEN1 | |
| SCHEMBL3888992 | 0.74 | MAPT (0.37) | MAPTRAB9AALDH1A1MEN1LMNA | |
| SCHEMBL2991244 | 0.74 | KIF11 (0.51) | RAB9ANPC1KMT2AKIF11 | |
| SCHEMBL2994541 | 0.72 | EPHX2 (0.47) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL7063953 | 0.71 | DDX3X (0.36) | MAPTRAB9APEPDALDH1A1NPC1 | |
| SCHEMBL55828 | 0.69 | GAA (0.42) | MAPTPEPDALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216138-A | With vinyl sulfonyl group | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |