Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464495 | 0.78 | PDE4D (0.60) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL9464226 | 0.73 | CYP1A2 (0.52) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL9464043 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1MAOACYP3A4CYP1A2 | |
| SCHEMBL9464064 | 0.72 | MAOA (0.45) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL9464056 | 0.69 | MAOA (0.47) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL15070027 | 0.66 | ALOX5 (0.40) | KDM4EALDH1A1CYP3A4PDE4DHSD17B10 | |
| SCHEMBL4194826 | 0.64 | ALDH1A1 (0.60) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| Luvangetin SCHEMBL14511557 | 0.64 | PDE4D (0.62) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL7478427 | 0.64 | MAOA (0.51) | KDM4EALDH1A1MAOACYP3A4MAPK1 | |
| SCHEMBL4185977 | 0.63 | KDM4E (0.68) | KDM4EALDH1A1MAOACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216176-A | 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor | LEHIGH UNIVERSITY (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1990008529-A2 | 7-ALKOXYCOUMARINS, DIHYDROPSORALENS, AND BENZODIPYRANONES AS PHOTO-ACTIVATED THERAPEUTIC AGENTS AND INHIBITORS OF EPIDERMAL GROWTH FACTOR | LEHIGH UNIVERSITY (US) | 1990-08-09 | — | — | WO | disclosed |